Generally speaking, videogames don't cause real bodily harm. But this X-ray, sent to us by a physician, proves that God of War III can break actual bones.
I had a patient who was so caught up in playing God of War III that he rolled over his hand with his knee and broke two fingers. The radiograph is attached (with his information omitted and arrows that point to the fractures). First time I've seen such an extreme gaming injury.
But in all actuality, it's probably just the first time someone admitted to such an extreme gaming injury.
Protip: If you ever break your hand doing something no sturdy person would break their hand doing, be sure to namedrop "bar fight" and "minotaur."