The web-based tool works on the iPad 2 (yay!) and all iOS devices running iOS 4.3.3. So what are you waiting for, fire up your iOS device and point your mobile browser to JailbreakMe.com to get the ball rolling. As always, proceed with caution and Happy Jailbreaking!
Update: Comex did mention that his site was having web-caching issues and some people are reporting an error when they try to download the jailbreak files. He tells everyone "If it doesn't work, try tomorrow :p."
You can keep up with Kelly Hodgkins, the author of this post, on Twitter.