Lensbaby has a pretty good track record in making lenses which allow you to take photos with all manner of wacky focus effects. Now, it's targeting the budget end of the market by launching the Spark, an $80 lens that turns your DSLR into a selective-focus shooter.
Capable of attaching to a Canon or Nikon, this 50mm lens features a fixed f/5.6 aperture and focuses from 13-inches to infinity. All you do is squeeze the unit to focus and tilt it on its axis to move the "sweet spot" on the fly. The result should be images packed with the kind of focus effects you normally use Photoshop to achieve.