<![CDATA[Gizmodo: dna]]> http://tags.gizmodo.com/assets/base/img/thumbs140x140/gizmodo.com.png <![CDATA[Gizmodo: dna]]> http://gizmodo.com/tag/dna http://gizmodo.com/tag/dna <![CDATA[Nanoparticles Can Rip Your DNA Apart Without Ever Touching It]]> If I could visualize nanoparticles, I'd think of them as crime bosses because apparently they can mess with DNA without ever having direct interaction. Like a true godfather, a nanoparticle commands obedient molecules to do the dirty work.

Researchers aren't entirely sure just how the whole process works, but they have observed the resulting damage of nanoparticles signaling a hit on DNA. They suspect that the events might go differently in situations other than a lab test and that the interaction could be used to deliver medicine or target cancer cells. Either that or further nanoparticle deaths.

While they sort out the details, I'm just gonna stick to being a bit scared that I'll get a package of fish if I upset any nanoparticles anyway.[Pop Sci]

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<![CDATA[Scientists Mapping Out 10,000 Animal Genomes For "Genetic Zoo"]]> On the tail-end of news that all of the HIV genome and 98% of the pig genome has been decoded, scientists are announcing that they've got a plan to collect and sequence the DNA of 10,000 vertebrate species.

Over 68 scientists worldwide are participating in the Genome 10K Project, the results of which would not only bring understanding of changes in species but also "allow predictions of how certain species might respond to climate change, pollution, new diseases and competitors." There's great potential to discover more about genetics with this project, but I have a sneaking suspicion that at least one of those scientists is in it for the DNA scavenger hunt through zoos. [Genome 10K via Pop Sci]

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<![CDATA[DNA-Inspired Closet Is As Space-Efficient As It's Twisted and Curvy]]> Irina Alexandru's design is more of a coat hanger than a closet, but it's intended to allow for the maximum amount of clothing hangers in the smallest amount of space. I just plain like the curvy double helix design.

For those who are having flashbacks to biology class: Yes, a double-helix is actually nature's clever way of squeezing a heck of a lot of genetic information into a tiny coiled pattern. It's somehow almost fitting that the same design would make for efficient clothing storage, too. [Core77]

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<![CDATA[Customize Your iPhone With Your Own DNA]]> As if my iPhone didn't have enough of my DNA in the form of grease fingerprints, dead skin cells, and other precious bodily fluids, now I can add some more of it in wallpaper form.

French DNA laboratory Helys can do it for you. It works like this: Pay $147 and they will send you a DNA sampling kit. Send them back your DNA, choose a preferred tonal range, and they will make your genetic print into pixel form. Two weeks later, you will receive a 320 x 480 pixel picture in your email.

Of course, what Helys is not telling you is that this is all part of a secret plan by the French government to have a record of all our DNA. And with it, they will create a mutant cheese that will kill everyone in the planet who is not French or drinks Vichy water. I warned you. Don't come back later whining about it when your arteries explode because of the killer mutant cheese. [Helys via CNET]

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<![CDATA[Mighty Mouse Has One Less Gene, Lives 20% Longer]]> Sorry, Apple. Researchers have already created a mightier mouse: By deleting a single gene from a mouse's genetic makeup, they've enabled it to suffer fewer age related ailments and live 20% longer. On humans, that'd be about 16 bonus years.

So what exactly did those crazy scientists do? They bred mice with the "gene that produces the protein S6 kinase 1 (S6K1)" disabled. The effects of this are a bit extreme:

The change mimicked the effect of keeping the mice on a calorie-restricted diet. Severely restricting the diets of yeast, bacteria, mice and primates have granted these animals unnaturally long lives. For humans, however, maintaining a diet of near starvation would be difficult at best

That last part's the bad news so far, but researchers are conducting further studies particularly targeting the S6K1 protein as it seems to have a direct link to longevity in mice. There are hopes that the benefits will one day be reproduced with drugs so that we don't have to starve ourselves for longer lives and prettier looks.

I do hope that the boys reading aren't too obsessed about anti-aging though, because the last bit of bad news is that "only the female mice benefited" in the study. Sorry, guys. [Discover]

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<![CDATA[IBM Examining Microchips Built On DNA "Origami" Nanostructures]]> From the "at least 10 years out" category of microchip fabrication comes word that IBM is working to reduce future costs and microchip sizes by using DNA.

Yes, that's correct: The building blocks of life could one day contribute to your virtual reality headshot in Halo 28: Master Chief Comes Back From the Dead for the 12th Time.

IBM's early stage research combines the DNA double helix and, unsurprisingly, nanotechnology to build frameworks for theoretically smaller and less expensive microchips.

"This is the first demonstration of using biological molecules to help with processing in the semiconductor industry," said IBM research manager Spike Narayan. "Basically, this is telling us that biological structures like DNA actually offer some very reproducible, repetitive kinds of patterns that we can actually leverage in semiconductor processes," he said.

But like I said, ten years out of more before the same genetic building blocks found in all of us are also powering the supercomputers of the future. [Reuters]

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<![CDATA[Genome Sequencing Gets 99.9833% Price Cut]]> Dr. Quake of Stanford University only needed $50,000 and a month's time to complete a genome sequencing process which previously took $300 million, over 250 people, and several years. How cheap would Windows 7 be with this guy's cost-cutting?

Dr. Stephen Quake and his team used a "commercially available, refrigerator-sized instrument called the Helicos Biosciences SMS Heliscope" to sequence Quake's genome.

This machine, also known as a single molecule sequencer, is incredible. Instead of needing to generate thousands upon thousands of copies of a person's DNA, it chops the fundamental units of DNA, the bases, into short strands, slaps them onto a specially treated glass plate, and proceeds to read the sequences.

After these steps are completed, a series of computers will assemble all the DNA strands into a genome while comparing it to previously compiled genomes. According to an algorithm used by the team, this sequencing process results in genomes which are about 95% complete. (This is on par with previous sequencing technology.)

While Quake's research is important in what it represents: genome sequencing could become something used by regular health care providers to diagnose genetic predispositions to diseases (or maybe just figure out if someone's genetic code "contains a form of a gene that has sometimes been associated with increased disagreeability"), it also does something curious: in shows a far larger decrease in cost than Moore's law alone would suggest. The combination of better processing with a far better algorithm resulted in this dramatic progress over the past eight years and we can't wait to see how the implementation of improved algorithms will continue to affect this trend. [Business Wire]

Photo by Helicos

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<![CDATA[Secret of Eternal Life, Better Sex Found in Mammoth Graveyard]]> Get ready for eternal life and better sex: Russians scientists working on a Siberian mammoth graveyard have found unknown bacterium DNA which, according to preliminary lab results, effectively extends mice's life-as well as other things.

According to Professor Anatoli Broushkov, their "set of tests and the results prove that simple organisms like fruit flies and mice live longer after being vaccinated with the ancient bacterium extract." Not only that, but the bacterium DNA super-vaccine actually increases mental alertness, physical capability, and sexual activity for both male and female mice. The females actually have had babies at an older age than usual: "Some elderly mice demonstrated a growth of physical, mental and sexual activity, while some females even had babies aged at the human equivalent of 70," said scientist Vera Samsonova.

The bacterium was found still living in the Siberian permafrost, next to frozen the mammoths and woolly rhinos, which the Japanese and Russian scientific teams are exploring in an effort to clone them back into life. Finding an unknown ancient bacteria still living in the permafrost came as a surprise to the Russian scientists, who were blown away by the preliminary analysis of the DNA and their lab experiments.

The team, however, is not claiming an immortality potion yet: They are aiming at extending life at least ten years if everything goes well. The results are so good that it is already attracting the interest of investors.

The only thing that has me thinking here is that these bacterium were found next to extinct prehistoric animals. But hey, I'm all for injecting myself ancient DNA that can either increase my virility and extend my life. Or make me grow huge tusks and plenty of hair. In both cases, it's a win. [Daily Mail]

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<![CDATA[DNA Strands Converted Into Tiniest Fiber Optic Cables For Optical Computing]]> Future optical computers that use light instead of electricity will need nano-scale pipes to transfer photons—analogues to the individual transistor's in a traditional circuit. And for that, scientists for the first time have used human DNA to build the smallest fiber optics cables yet created. And as is typical with organic computers, said cables are capable of assembling themselves.

The technique, spearheaded by Bo Albinsson at Chalmers University of Technology in Gothenburg, Sweden, encodes DNA in a way that, when mixed with light-receptive molecules called chromophores, self-engineer themselves into a natural photo-sensitive wire that can accurately transmit light—similar to those found in some algaes. The technique may also someday be used for artificial photosynthesis systems that may power next-gen solar cells. [New Scientist, Image: DNA visualized in a cDNA microarray from Wiki Commons]

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<![CDATA[Craigslist Armored Truck Thief Gets Nabbed]]> You may recall a story a couple of months ago about a man who successfully robbed an armored car by hiring decoys on Craigslist, then fled the scene by floating down the Skykomish River in Washington on a inner tube. It's a great heist story—straight out of the climactic scene in the Thomas Crown Affair. However, unlike Pierce Brosnan, this criminal won't be jetting off to live out the rest of his days with some insurance investigating MILF. The culprit was nabbed by police this week outside of a Target store using good old fashioned DNA evidence. It was almost the perfect crime. [SeattlePi via Wired]

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<![CDATA[Direct Note Access Music Software Now Even More Revolutionary]]> Back in April we discovered a new music recording program from Celemony Software that could potentially revolutionize the music industry. It allows recording engineers to isolate and manipulate individual notes (as opposed to an entire chord) from a performance (no matter how lame) and turn it into a flawless piece of music. Celemony has revealed new details about DNA that claim the program will be able to handle "complete mixes (rather than a simple piano progression, for example)," but stresses that the more complex the job, the less likely you are to isolate individual notes.

Melodyne Plugin 2, the first product to incorporate DNA, has also added the ability to cut and paste / overlap notes and chords individually or in sequence. Unfortunately, the release date of the plugin has been pushed back to 2009—but Celemony has promised to run a public beta testing program prior to launch so people can familiarize themselves with the technology. The fact that it is getting pushed back sucks, but it's better late than never. After all, the recording industry needs a good kick in the pants to get their focus back on quality. [Music Radar]

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<![CDATA[Israeli City Using DNA Testing to Fight Rampant Dog Poop Problems]]> Nobody likes stepping in dog crap. That's why there are laws in most major cities that require you to pick up after your dog. Unfortunately, it's tough to enforce and many people just ignore it. The solution? Elaborate and expensive DNA testing, of course.

The Israeli city of Petah Tikva, a suburb of Tel Aviv, has just launched a six-month trial program that will have local dogs DNA tested so their droppings can be identified after being scraped off the bottom of your shoe. The system will work both as a way to punish poop-leavers as well as reward those who do their civic duty by cleaning up after their pooches. If you scoop up after your dog and leave it in specially marked bins along the streets, you'll be eligible for pet food coupons and dog toys. If it's found on the street, you'll be eligible for fines.

It's a pretty interesting idea, but I wonder if it's worth all the effort. Sure, clean streets are great, but how much does it cost to set something this elaborate up? I mean, how much are you going to have to pay the poor bastard whose job it is to go around analyzing dog crap from the sidewalks? Yikes. [Reuters]

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<![CDATA[Douglas Adams' Hitchhiker's Guide to the Galaxy Typewriter Up for Sale]]> See that battered old Hermes Standard 8 typewriter there, in a fetching shade of institutional brown? I'd practically saw my own leg off to own it. Why? Because I'm a huge Douglas Adams fan, and that battered old thing is the very typewriter DNA used to bring The Hitchhiker's Guide to the Galaxy to the world. A surprisingly analog gadget, for such a self-avowed technology fan as he. And get this: it's actually on sale by a British bookseller, as part of a package with a "fine" condition first-edition copy of Hitchhiker's. The package, complete with autograph on the typewriter lid, will set you back over $25,000. A vastly, hugely, mind-bogglingly big sum. But, boy... wouldn't it be worth it? [Abe Books via BBG]

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<![CDATA[Amazing Direct Note Access is Photoshop For Music]]> Charlie over at DVICE is a musician, so if he says this Direct Note Access is miraculous, we definitely believe him. Think of this software suite as Photoshop, but for music—able to change any note to any other note even if it's buried inside chords or other instruments playing simultaneously. Up until now, you could only change the entire chord, not individual notes, which would affect the general feel of the tune. But as you can see above in the video, DNA gives people much more control. [Celemony via Technology Review via Daily Swarm via DVICE]

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<![CDATA[Over the Counter DNA Paternity Tests Seem Like a Great Idea]]> After home pregnancy kits revolutionized stick peeing from an office to a home affair, the door was opened to the general public performing previously lab-only work on their own toilets. Identigene and Rite Aid have taken it one step further, allowing you to tell whether or not that kid is yours with a simple $29.99 kit (plus $119 lab fee) that includes three mouth-rubbing swabs. Results are obtained in the longest three to five business days you've ever experienced, but if you want a result that's actually "court admissible", you'll have to pay an another additional fee. And honestly, who would get one of these just out of curiosity and not have it be in preparation for some sort of custody battle? [DNA Testing via Gearlog]

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<![CDATA[Modular DNA PC Concept Lets You Build it Like LEGO]]> This modular DNA PC concept looks quite similar to the Bookshelf Microsoft ISDA design concept from a few years ago, but it's slightly different in that it's almost entirely made out of cubes. The core idea is the same: you've got a base "PC" that you add features and peripherals onto by attaching them together. Keyboard, storage, RAM, and other components are all interchangeable, which gives the final PC construction a bit of a kindergarden/LEGO look. Interesting, yes, but a bit too far-fetched to be really usable.

[Techpin via DVICE]

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<![CDATA[NEC Creates Mobile DNA Lab, Baby Daddies Run in Horror]]> Maybe we've been watching too many CSI reruns, but NEC's mobile DNA lab looks awesome. Not only does it bring portability to DNA analysis, but it even improves upon the typical versions. To complete its barrage of tests takes about 25-minutes &mdash and, by comparison, a typical DNA lab would take an entire day. NEC achieved this by significantly decreasing the time it takes to heat and cool the DNA sample during PCR amplification. And just think, if this thing takes off, the old "Lets send this back to the boys at the lab" line could finally be laid to rest. [Pink Tentacle]

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<![CDATA[Titanic DNA Watch Made From Actual Titanic Parts]]> Romain Jerome's Titanic DNA Watch doesn't just name itself after the movie—which we still refuse to see—it's made out of actual steel from the ship. Along with that, the watch face is painted black out of coal recovered from the wreck, and parts of it are made from platinum and other metals they could salvage.

We're guessing a watch made out of parts of a sunken ship won't be "affordable," but what better way to time exactly when it is Kate Winslet gets topless than this baby? Oh wait, people have already done that for you.

Product Page [RomainJerome via Wrist Dreams via Oh Gizmo]

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<![CDATA[Automatic Blood-Toxin Detection]]> A pair of scientists from the University of California at Santa Barbara and two high school students have developed a sensor that can detect cocaine in the bloodstream along with other biotoxins. The sensor can be built into portable devices and can perform the entire detection process real-time in just a few minutes. It works by creating an artificial DNA molecule that will react when a blood sample is applied.

This project isn t just focusing on toxins either. There are a lot of potential health care applications. The artificial DNA could be modified to react to blood samples containing specific diseases or even to detect what kind of prescription drugs are being used in emergency situations when the patient isn t able to communicate for themselves. The group has already been in discussion with several companies regarding licensing.

Sensor instantly detects cocaine in blood [News.com]

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<![CDATA[DNA Art]]> Picasso, Matisse, Van Gogh — make way for my DNA. DNA 11 is offering to create artwork based on your very own DNA, so now you don't need any talent to create truly one-of-a-kind masterpieces. A group of different sized pieces of your DNA is run on a type of "gel," which is then treated with fluorescent dye and an ultraviolet light. The result is a unique luminescent glow. A camera takes a picture of it, and ta-da, science makes art. And if it looks bad, well, you only have your genetics to blame.

Prices range from $800 to $1800, which is certainly pricey, but it's quite reasonable for an art piece that is unquestionably yours.

DNA 11 [DNA 11 via Reluct]

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