The big upgrades over the $300 Harmony 1000 are a new black anodized aluminum body and a now-customizable touchscreen. (Read about it more here.) Remember when silver was the upgrade color? Yeah, now it's black again—at manufacturers other than Apple even.
And I'm so sick of silver that they've totally sucked me in. Damn you and your clever anodized alunimum, Logitech! Damn you! [Newegg Thanks Ron!]