For his Mikenesses series, Adventure Time and Bravest Warriors cartoonist Mike Holmes drew himself (often accompanied by his cat Ella) in the styles of more than 100 different cartoonists and animators. It's a neat study that shows a real understanding of the styles—and it's also incredibly charming.
It looks like Mikenesses have been on pause for a while, but Holmes has tons of them up on his Tumblr. Here are just a few of them:
In the style of Quentin Blake:
In the style of Berkeley Breathed
In the style of Wallace and Gromit
In the style of George Herriman
In the style of Dr. Seuss Chuck Jones
In the style of The Powerpuff Girls
In the style of Graham Annable
In the style of Archer
In the style of Osamu Tezuka
In the style of Gary Larson
In the style of Rob Liefeld
In the style of Nicholas Gurewitch
In the style of Bill Watterson
Mikenesses [Mike Holmes Draws via MetaFilter]