CNET reviews the Evoluent VerticalMouse 2, a peripheral designed to ease the stress of mousing by making you hate mice altogether, apparently. Although the idea is sound, according to CNET, the execution is flawed, forcing you to hang your hand on the mouse against gravity, which is tiring. Plus it sounds like there are some manufacturing flaws, including loose rubber bits that get caught up in the scroll wheel. It seems you might be better off saving the $70 and just buying some Valium from your suburban apothecary.
Evoluent VerticalMouse 2 [CNET]