Kirby Reed, Scream 4 (2011); Scream VI (2023)
Tough and extremely horror-savvy, Kirby (played by Hayden Panettiere, soon after her rise to fame on Heroes, but before her run on Nashville) survived Scream 4, unlike most of her high-school pals—and despite losing what had to have been gallons of blood after meeting the wrong end of the killer’s knife. Panettiere’s been absent from screens for a few years, so it was a delight for fans of both her and the character to see she’d be bringing Kirby back for Scream VI.
