The Doctor Is In

Miles Morales’ post-credit scene directly sets up Marvel’s Spider-Man 2 by returning us to Norman Osborn and the in-stasis Harry, while also formally introducing us to a major Spidey character for the first time: Dr. Curt Connors, who is seen working on Harry’s cure, and disagreeing with Norman’s insistence that Harry be brought out of his mysterious stasis.
In Marvel’s Spider-Man, various passing comments and Easter-egg collectibles reveal that in this version of Spidey continuity, Connors had already inadvertently transformed himself into the Lizard in an attempt to regenerate his lost arm, becoming one of Peter’s first villains in his time as Spider-Man. Suffice to say his connection to Norman and Harry is going to lead to him having a big role in Marvel’s Spider-Man 2… including as the Lizard, as we’ve already seen footage of Miles and Peter battling the creature in the run up to release.