There's some talk that the new ROKR will have iTunes installed, something that everyone said would probably never happen again. However, because the E2 runs Motorola's Linux-based OS, which in turn can run iTunes, it seems plausible.
The original ROKR E1 flopped and rumors of Apple's move to make a mobile phone means that manufacturers will probably be kept away from the iTunes license for the time-being. However, if the E2 is a big enough improvement, there may be some hope. No mention of it on the Motorola page, though.
Product Page [Motorola]
Motorola ROKR E2 to Include iTunes After All? [MobileBurn]