If you're using a Hackintosh then you might want to hold off on the OS X 10.6.2 update, because for all its bug fixes, it lacks the Intel Atom support necessary for our beloved Hackintosh netbooks. Update.
Update: There appears to be some confusion regarding which sort of Hackintosh set up is affected by 10.6.2. If you are running something other than an Intel Atom-based netbook, you should be just fine, it's those relying on Atom-support who are in trouble with this one. [OS X Daily]