We've seen countless examples of how the humble tube of toothpaste can be redesigned so every little drop can be put to good use, but designer Catherine Werdel's toothbrush-squeezer might be my favorite yet. [Catherine Werdel via Fancy via OhGizmo]
The only thing novel about the mentioned squeezer is that it looks like a toothbrush and thus cute. But with it being so long, you either have to remove it every time (and store it with the other toothbrushes) or stand up your toothpaste tube like in the photo (assuming your tube has the wide-mouth pop-off caps). I suppose you can roll the tube with the above squeezer, like opening an old fashion can, but there is no mechanism to keep it in place afterwards.
Personally, I just roll it and keep it in place with a binder-clip. If you want a gadget, I found this roller-type device.