I updated to 10.4.7 night before last. Ever since, I've had increasingly frequent lock-ups on my system. They aren't hard locks, insomuch as I can still move the mouse around, but I can't click or input any text until I reboot the machine. It's not a specific app that's doing it either—it'll do it from a cold boot just sitting at the desktop.
Anyone else had any problems with the 10.4.7 update? It's always nice to have some backup when you call Apple's customer service when they try to tell you it's an isolated problem.