Indole, an organic chemical compound that’s found in our gut and contributes to the smell of poop, increases the healthy lifespan of worms, flies, and mice, according to new research. Scientists say this likely applies to humans as well, and that this stinky substance could eventually be used to delay age-related…
Professor S. Jay Olshansky once told Gizmodo, “In the world of aging sciences, if you want to live a long life, choose long-lived parents.” So genetic markers linked to longevity are interesting as hell. But if you’ve got the wrong genes, then the wrong moves might do you in.
Imagine a world in which the only possible way to die was through a sudden accident, such as a car crash, falling down the stairs, or getting struck by lighting. How long could we expect to live in such a world? According to an eye-opening simulation, a very, very, long time, indeed.
Depriving ourselves of food to the point of near-starvation doesn’t sound very appealing, but it could prolong our lives and prevent the onset of age-related diseases. A combined analysis of two long-running studies shows that caloric restriction does indeed work in monkeys, hinting at its potential to work in humans.…
The oldest human to have ever lived died at the age of 122—and that was nearly 20 years ago. A recent analysis of global demographic data suggests this may very well be the maximum age attainable by humans, and that it’s extremely unlikely anyone will ever live much beyond this advanced age. That is, unless we science…
A compound called nicotinamide mono nucleotide (NMN) has been shown to slow down the aging process and extend the lifespans of mice. We’re about to find out if it does the same thing to humans.
By flushing out cells worn with age, researchers from the Mayo Clinic have extended the lifespans of mice by as much as 35 percent. It’s an encouraging finding that could eventually lead to similar therapies in humans.
What if “life in prison” could mean 100 or 200 or 400 years? Does that change the way that sentences are doled out? What happens when a person gets out of prison?
Researchers from the Scripps Research Institute and the Mayo Clinic have developed a new class of drugs that were shown to significantly slow the aging process in animal models. Remarkably, dramatic improvements were noticeable just days after treatment.
Even 10 years ago, the idea of reversing aging and conquering human mortality was still fringe science, seen as snake-oil research by most scientists, large pharmaceutical companies, and the public. What a difference a decade makes. Anti-aging science is poised to become a major industry in the biotech world.
Scientists from Stanford Medical Center have devised a technique for extending the length of human telomeres. It's a breakthrough that could eventually result in therapies to treat a host of age-related diseases, including heart disease and diabetes. It could also result in longer, healthier lives.
The antioxidant resveratrol, which is found in red wine and other foods like nuts and soy, is known for its ability to decrease incidence of heart disease and other illnesses, leading some to call it the "elixir of youth." Researchers at the Scripps Research Institute now have an explanation for how it works.
Very few people live to be 110 or older. Incredibly, many of these "supercentenarians" do virtually nothing to stay healthy or fit, leading scientists to speculate that certain genes are responsible. But recent analysis of the human genome suggests this is an oversimplification.
Researchers at the Salk Institute have discovered a toggle switch for aging cells. By controlling the growth of telomeres, it may eventually be possible to coax healthy cells to keep dividing and generating even in old age.
A handful of girls diagnosed as having 'Syndrome X' seem to defy one of the biggest certainties in life: aging. Scientists who are working to understand this rare condition say it could inform our efforts to radically extend the human lifespan.
Prior to her death at the tender age of 115, Hendrikje van Andel-Schipper was the world's oldest woman. Recently, scientists had the opportunity to study her blood — and what they discovered could have serious implications to the future of rejuvenation therapies.
For the first time ever, biologists have regenerated an organ in a living animal. They did so by manipulating a single protein in elderly mice that makes their bodies rebuild their thymuses, an organ of the immune system. It's the first time an organ has been repaired with a chemical trigger and not via stem cell…
The fascinating short documentary We Will Live Again goes inside the Cryonics Institute, where we meet the people behind the freezing process and witnesses (non-explicitly) the acceptance of its hundredth client.
A long-running study is re-affirming the life-extending benefits of calorie-restricted diets. It overturns a study from 2012 indicating otherwise. The 25-year experiment shows that rhesus macaques, when eating 30% less than normal, are twice as likely to live beyond those who could eat whatever they want.
Supercentenarians are rare people who have reached the age of 110 and remain fit. Amazingly, many of them never get sick, despite having some bad health habits in some cases. Scientists say it all comes down to genetics — which could lead to a gene therapy that promotes longevity. Here's how super-c's will help us…