Psilocybin

Magic Mushroom Ingredient Passes Major Test, Paving Way for FDA Approval

In two large-scale trials, Compass Pathways' proprietary form of psilocybin improved people's depression symptoms better than controls.

Health Ed Cara Feb 18

We Can Now See How Psilocybin Changes the Brain

Scientists tracked changes in brain activity after people took a large dose of psilocybin, finding clues on how the psychedelic drug might help treat depression.

Health Ed Cara Jul 17

Emerging Psychedelic Mushroom Alternative More Toxic Than Fentanyl, New Research Suggests

Researchers are urging the public to be cautious of misleading supplements that contain Amanita muscaria instead of the expected psilocybin.

Health Ed Cara Jun 11

‘Designer Shrooms’ Could Be Coming as Scientists Unlock Genetics of Magic Mushrooms

The findings could help researchers develop mushrooms with unique psychedelic compounds.

Health Ed Cara Dec 5

Phase II Study Finds That Psilocybin Plus Therapy Can Help Treat Depression Symptoms

The researchers found a single dose of psilocybin combined with therapy seemed to produce a "rapid and sustained antidepressant effect" for up to six weeks.

Health Ed Cara Sep 1

Doing Shrooms Might Have Improved a Man’s Color Blindness, Doctors Say

A man's experiment with psilocybin-containing mushrooms seemingly left him with long-lasting improvements in his red-green vision.

Health Ed Cara May 5

Largest Trial Yet Shows Promising Results for Psilocybin as Depression Treatment

People who got a single, large dose of psilocybin along with psychological support improved significantly on average up to three weeks later, the trial found.

Health Ed Cara Nov 3

Psilocybin Therapy Changes Brain Wiring in Depressed People, Study Finds

In clinical trials, people taking psilocybin showed changes in brain patterns associated with depression.

Health Ed Cara Apr 11

It’s a Good Week for Drugs

Californians, your state senators (who are not your mom), see that you trip balls and/or go on spiritual journeys, which is just fine. On Tuesday, the state senate voted to pass a bill that would legalize the possession and ingestion of psilocybin and psilocin, ketamine, LSD, MDMA, DMT, mescaline, and ibogaine. Ya know, shrooms, acid,…

Tech News Whitney Kimball Jun 2

Scientists Closer to Creating Psychedelic-Like Drugs That Work Without Hallucinations

In a new study this week, researchers describe their work with experimental compounds that could offer the mental health benefits of a psychedelic drug, without causing people to trip out. Their early research, so far only conducted in mice, might someday provide people with more first-line treatments for illnesses like depression. Psychedelics are currently being…

Health Ed Cara Apr 29

Psychedelic Mushrooms Grew in a Man’s Veins After He Injected Them

The man was hospitalized for 22 days but survived.

Health Ed Cara Jan 12

Drugs Won the Election

With ballots for the U.S. 2020 presidential election still being counted in several states, it’s possible that we won’t know that outcome for quite some time. But one clear victor emerged in another fight: the drug legalization movement. In multiple cities and states, in both red and blue areas, people voted to legalize or decriminalize…

Health Ed Cara Nov 4

Inside the Fight to Legalize Psilocybin Therapy in Oregon

On a sunny September afternoon in Portland, volunteers pour into a Zoom conference room. They’ve come for a weekly update from Oregon’s Yes on Measure 109 campaign—a measure which would create the world’s first market for psilocybin-assisted therapy. The pandemic prevents them from knocking on doors to reach voters. But that has not dampened their…

Tech News Mason Marks Oct 22

Santa Cruz Is the Latest U.S. City to Decriminalize Magic Mushrooms

As cannabis becomes widely decriminalized, another drug-legalization movement in the U.S. is picking up steam. On Tuesday, the city council of Santa Cruz, California voted to decriminalize the use of psychedelic mushrooms within its borders. It’s now the third city in the U.S. to have done so. The decision won’t exactly make magic mushrooms legal…

Health Ed Cara Jan 29

‘Magic Mushroom’ Ingredient Inches Closer to Becoming a Depression Treatment

A future where a key ingredient of psychedelic mushrooms called psilocybin is regularly used to improve our mental health is none too far off. This month, the Food and Drug Administration (FDA) granted a “breakthrough therapy” designation to a non-profit company developing psilocybin as a treatment for clinical depression. The label is intended to speed…

Health Ed Cara Nov 27

‘Magic Mushroom’ Chemical Harvested From Bacteria For the First Time

New research shows that psilocybin—the psychoactive compound that puts the magic in magic mushrooms—can be made by bioengineered bacteria, highlighting a potential new way of mass-producing the valued chemical. For the first time, scientists have demonstrated the possibility of coaxing a prokaryotic host, the bacterium Escherichia coli, into producing psilocybin. To do so, a team…

Biology George Dvorsky Sep 30

Oakland Becomes Second U.S. City to Decriminalize Magic Mushrooms

For people who have not been following the fight to legalize psilocybin, it may seem like the movement to decriminalize magic mushrooms sprung up from the earth overnight. The Oakland City Council on Tuesday voted unanimously to decriminalize magic mushrooms and other psychoactive fungi and plants, ordering law enforcement to stop the prosecution of possession…

Health Jennings Brown Jun 5

Denver Vote to Decriminalize Psilocybin Mushrooms Appears to Snag Last-Minute Victory [Corrected]

Correction: 5/8/2019 at 9:45 p.m. ET: Turns out magic mushrooms really do sneak up on you! An earlier version of this story, citing preliminary results and media reports, stated that Measure 301 failed. In a twist that appears to have surprised most of the national media—and that did not occur until late Wednesday afternoon—Denver’s psilocybin…

Health Tom McKay May 8

The Main Ingredient in Psychedelic Mushrooms Is Closer to Becoming an FDA-Approved Depression Treatment

The active ingredient that makes magic mushrooms so magic—the psychedelic drug psilocybin—is one step closer to becoming a legal treatment for difficult cases of depression. This week, the company Compass Pathways announced that it had received the Food and Drug Administration’s Breakthrough Therapy designation for its psilocybin-based treatment. The designation will fast track the FDA’s review…

Health Ed Cara Oct 25

Magic Mushroom Chemical Appears to Physically Change Depressed Brains

Magic mushrooms are a strange drug. They’re one part illegal music festival enhancer, one part promising treatment that could have important medical applications. That second use continues to look more and more promising. A new study from researchers in the United Kingdom and South Africa monitored the brains of folks trying psilocybin, the magic mushroom…

Tech News Ryan F. Mandelbaum Oct 13

Psilocybin

Magic Mushroom Ingredient Passes Major Test, Paving Way for FDA Approval

We Can Now See How Psilocybin Changes the Brain

Emerging Psychedelic Mushroom Alternative More Toxic Than Fentanyl, New Research Suggests

‘Designer Shrooms’ Could Be Coming as Scientists Unlock Genetics of Magic Mushrooms

Phase II Study Finds That Psilocybin Plus Therapy Can Help Treat Depression Symptoms

Doing Shrooms Might Have Improved a Man’s Color Blindness, Doctors Say

Largest Trial Yet Shows Promising Results for Psilocybin as Depression Treatment

Psilocybin Therapy Changes Brain Wiring in Depressed People, Study Finds

It’s a Good Week for Drugs

Scientists Closer to Creating Psychedelic-Like Drugs That Work Without Hallucinations

Psychedelic Mushrooms Grew in a Man’s Veins After He Injected Them

Drugs Won the Election

Inside the Fight to Legalize Psilocybin Therapy in Oregon

Santa Cruz Is the Latest U.S. City to Decriminalize Magic Mushrooms

‘Magic Mushroom’ Ingredient Inches Closer to Becoming a Depression Treatment

‘Magic Mushroom’ Chemical Harvested From Bacteria For the First Time

Oakland Becomes Second U.S. City to Decriminalize Magic Mushrooms

Denver Vote to Decriminalize Psilocybin Mushrooms Appears to Snag Last-Minute Victory [Corrected]

The Main Ingredient in Psychedelic Mushrooms Is Closer to Becoming an FDA-Approved Depression Treatment

Magic Mushroom Chemical Appears to Physically Change Depressed Brains

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