"Batman Killed Harvey Dent"
Who: Commissioner Gordon
Where: The Dark Knight
What: EDIT: Flipped the lies because the commenters are right, "Batman killed Harvey Dent" is a much bigger lie than Ra's al Ghul is Henri Ducard. However we leave Ra's al Ghul's real identity from Batman Begins, and The Joker's fib about the real location of Rachel as honorable batman mentions.

"My name is Henry Gale. I'm From Minnesota!"
Who: Ben Linus
Where: Lost
What: The first of many lies from old Ben Linus. He even had us going for a little bit. But we're not sure what was creepier, that he could lie so convincingly, or that there actually was a Henry Gale, and he was dead.

"I know where it is! Earth - the most guarded secret we have. The location was only known by the senior commanders of the fleet, and we dared not share it with the public. Not while there was a Cylon threat upon us. For now we have a refuge to go to. A refuge that the Cylons know nothing about! It won't be an easy journey. It will be long and arduous. But I promise you one thing. On the memory of those lying here before you, we shall find it. And Earth will become our new home. So say we all!"
Who: Commander Adama
Where: Battlestar Galactica
What: Lied about knowing where Earth is. Lied about Earth even being a real thing, but he gave the crew something to live for. A big lie for a good cause.

"All is accomplished the City Watch is yours."
Who: Petyr Baelish
Where: Game Of Thrones
What: Littlefinger lies and lies and lies and lies and lies. But his best lie thus far put Ned Stark's head on a platter for King Joffrey. Ah well, he did warn Ned not to trust him.


"Sorry Kid."
Who: The Oracle
Where: The Matrix
What: The Oracle tells Neo he's not The One, or at least "not in this lifetime." Which makes sense when he dies and comes back as, the One. I guess she tells you what you need to know, just in a really fucked up way.

Who: Everyone
Where: Logan's Run
What: The time of "renewal" is met with great cheers, too bad it means that person has to die.

"Soylent red and Soylent yellow, high energy vegetable concentrates, and new, delicious Soylent Green."
Who: The government
Where: Soylent Green
What: It ain't delicious, it's people.


"Oh, laddie. You've got a lot to learn if you want people to think of you as a miracle worker."
Who: Scotty
Where: Star Trek: The Next Generation
What: Scotty admits he often lies about how much the engines can take, how long it will take to fix them and more, just to make himself look good.

"Kick His Ass."
Who: Xander Harris
Where: Buffy the Vampire Slayer
What: Xander, not a fan of Angel, buries Willow's message about a potential spell that could save Angel. Instead, he tells her to kick his ass, and Buffy winds up killing her boyfriend (sort of).

"Darth Vader betrayed and murdered your father."
Who: Obi-Wan Kenobi.
Where: Star Wars: A New Hope
What: How about, Darth Vader is your father and I cut off his legs and left him to die on a volcano planet. Also, you have a twin sister. This lie is the first BIG Star Wars lie, second maybe to the Emperor telling Anakin he killed Padme in his anger. But the prequels aren't real movies, so this is number one.

"We Come From France."
Who: Coneheads
Where: Coneheads
What: Not a huge lie, more the dedication to the lie. FRANCE FRANCE WE COME FROM FRANCE, that makes it delightful, and memorable.