lazy bastards

Eat less calories, move more. Common sense FTW?

Seriously? This is like big news!

@Git Em SteveDave: you would think that telling people over and over to MOVE THEIR ASSES would get the message across but I've found it doesn't. I just shake my head and say to myself "yup...you're going to die before me". that tends to make things better.

Bring on the partially de-fatted beef fatty tissue. Num num.

What power?! Is that some sort of Hippy thing!? Where's my loaded steak burger?

@Walter:
it's analogous to yelling at smokers constantly. we don't listen, we're just waiting for science to grow us new lungs and cure cancer. or not. we're not very particular on the whole dying thing.

"Screw the testing, just bring us the drugs and we'll take the risk."

A true Frucci post...

"There'll be no need to exercise when you'll have easy access to a drug that makes trans-fat-laden fast food less appealing while it burns away the vast reserves of fat your body has been storing away all these years"

I liked this idea better the first time, when it was called "cocaine".

Side effects may include incresase sexual urges and compulsive gambling.

That seems to be a common side effect these days

lol, does anyone else have the banner ad for chili's bottomless lunch? Kinda ironic

@Git Em SteveDave:

"Common sense FTW?"

yeah, sure, but um... WHICH world? Earth? hahahaha no seriously. Which world?

Cocaine? Are you crazy?

Cocaine is way too expensive. :P

I wonder, if this drug is released for human use... will it affect the cost of food? After all, less appetite = less demand + more supply = lower prices. Probably, although the question is how much. How much of the food consumed in the world is a result of gluttony and not hunger? Hmm.

@Ghede: Intersting thought. Exactly how much of the "average" American diet is for sustaining oneself, and how much is a result of the drug munchies and shitty cereal advertising?

Now you just have to overcome the slovenly tenancies that made you fat to begin with.

@Bowler Hat:
cocaine is too expensive? maybe 20 years ago. in the bay that shit is everywhere. $30/ gram last i heard.

Yes, mice are just a step away from humans.

now what I really want to know is...can I take my new pill while stuffing my face with donuts, sitting at a computer desk, drinking a calorie loaded energy drink?

because if not...no way I am getting off my ass to go pick up this prescription.

@nutbastard: Our man on the street!

I've always been fine on 1,000 calories or so per day for a long time. I eat twice a day, about a handful of food each time. Were it not for beer i'd be a complete stick figure. As it stands im 6'1" and 155lb. It's good to be young : )

So we have to eat the mice to get the enzyme right?

@DustyButt:
yeah i've grown up and gots me a real job, but i still kick it with the same losers i went to high school with.

@nutbastard: um I thought 6'1" 155 lbs is a stick figure?

@nutbastard: You forgot to add that part about liking long walks in the park and the smell of rain.

@nutbastard: Or you'll do what John Wayne did. He told them to take out his lungs, and he would grow gills and learn to breathe like a fish.

Most drugs do not translate from animal models into humans. It will be interesting to see the results of actual human trials. It's like cancer drugs. Many work in mice, few work in humans.

I like how the Chili's "bottomless lunch" deals pops up in the Giz ad bar... Excellent ad placement guys!!!

Never mind the fairly obvious consequences of not having stores of energy when you unexpectedly need to be going on that that long wilderness expedition... Say, after some sort of asteroid impact or other global catastrophe. That drug could spell doom for the entire species! Mark my words, only the fat ones will survive...

Now... Where'd I put that jar of mayonnaise?

@ninjagin: actually for an IND submission (approval to test in humans) the FDA would require a basic battery of studies, a few in mice or rats, followed by a few in either dogs or monkey's generally if you're talking about something that has an affect on enzymes they will much rather see the monkey studies than dog studies.

@mykalt45: this is correct in a way, 75% of the compounds tested in animals fail to live up to expectations. A lot more goes into it than just the fact that it doesn't translate well, but as a rule most compounds fail. That's why the few that do get through and actually make it to market are fairly costly, they're paying for all of the failures, just the simple battery of studies required by the FDA in animals for an IND submission run in the millions of dollars.

Cause cancer? U means aids. that how jeared did it.

@nutbastard: you mean the stuff cut with baby laxative?

"makes trans-fat-laden fast food less appealing "

Don't mean to be terribly harsh, but wouldn't a glance in the mirror do the same thing?

@nutbastard: Heh, I'm only 4" shorter, eat 2000 cals a day, and 30 lbs lighter. Stick that to your 'it's good to be young' theory. Nah nah!!

@McLucky: Hmm, if being healthy and not eating those disgusting crap concoctions they serve you in the drive through is grounds to be called a stick figure, than count me in. SOMEBODY needs to pull down the nations fat average... and live past 50.

There is already a drug on the market that does this, it's called Dexedrine. They use it to treat ADD (which Is why I have it), side effects include loss of appetite and increased metabolism. They used to use it in diet pills before it became a controlled substance. When you give it to a person who really does have ADD (not someone who's just been slapped with the label because they can't behave themselves) it lets them focus, and keep their temper under control. Give it to someone who doesn't have ADD and it's Speed, and has the opposite affect. And if you overdose, your heart will explode.

@Walter: Don't be too sure of that. Guy I know died about six months ago... 55 years old, in good health, ate right, rode a bike to work every day (~15 miles round trip), no history of heart problems in the family... had a heart attack and died.

My dad, 56, overweight, diabetic, gout, hypertension, etc, etc. Still going fine.

His father (my grandfather) had three heart attacks, a bad valve in the heart, two strokes, diabetes, hypertension and lived to 75.

@nutbastard: There's a reason it's also known as the Yay Area.

@something_unique_and_descriptive: It pretty much acts like speed either way. I don't like it, I LOVE IT!

@nutbastard: f*in smokers. stink up my life whenever they're around (even when not smoking)...

You want free choice (to smoke)? I want free choice NOT to smell smoke!!!

@Rodime: I'd like the choice of not looking at rotund people, but I guess we need to be reasonable, don't we?

OUTLAW FARTS NOW!

@Rodime: I'd like the free choice to not have you wasting my parking spaces too. I guess we'll all just have to learn how to get along (without legislation), won't we?

[www.milkduds.com]

Oh baby, now I can have food and sex (well that probaly burns calories) calorie free?

(Imagines all the whipped cream coated possibilities....)

the best way i've found to lose weight is to get a massive throat infection that causes pain when eating. so far i've dropped 3 pounds this week.

@Git Em SteveDave: Denis Leary likes it when you recycle.

@Goodnightbabytron: I can pretty much do "No Cure For Cancer" karaoke. In High School, my "theme" song was Asshole. I can sing it from memory. Whenever I hear someone say "You know what I'm gonna do...." I start singing the song in my head.

I thought there was already a drug that does this?

It's called Amphetamine..

And i'm prescribed it for my A.D.D lol.

I have no urge to eat anything ever, my heart rate is constantly increased causing me to burn calories more than usual. My attitude is much brighter and I can start and finish tasks easier :).

I'll believe it once its proven to be effective in humans. Anyone remember the leptin protein? Manipulating it in mice worked wonders in controlling body weight, turns out it wasn't expressed on nearly the same level in people. If everything that worked in mice worked in people we would have solved countless problems by now.

So, "diet and exercise" is great and all. But I eat a low-carb diet. I exercise *three hours* a day, five days a week. I weigh 270 pounds and am not losing any. It's INCREDIBLY condescending the way people dismiss any new weight loss solution by implying that fat people are inherently lazy.