Variety reports that the Oscars are considering passing over Brad Pitt's performance in The Curious Case Of Benjamin Button for a Best Actor nod, because his acting was enhanced by special effects. Especially in the early scenes where he's an old-man infant, some critics say he's more of an animated Gollum-esque figure than an actual actor. Variety wonders whether Paramount did too good a job of exposing the movie's makeup and CG wizardry in the promotional campaign, and that biased Pitt's critics against the role. I found Pitt's performance in the film somewhat underwhelming, but it was typical of the types of performances that often win an Oscar. To deny him one simply because his performance involved special effects is misplaced snobbery of the worst kind. [Variety]
This doesn't strike me as a case of genre bias, just an understandable confusion where the acting ends and the sfx begin. It's a tricky issue, which is likely to arise again and again until they come up with a special award for Best Motion Capture Performance or something.
Lord knows the Academy has given sf films short shrift in the past, but I think you're reaching in this case.